Egharevba, Osas Godshelp and Johnson, Divinefavour Chinaza and Dosumu, Olutola Omotayo and Oluyori, Peter Abimbola and Afolabi, Tokunbo Yemisi and Akinyomade, Owolabi and Ajanaku, Oluwatoyin Christiana (2025) Qualitative & Quantitative Phytochemical Constituents, GC-MS Analysis and Antibacterial Activity of the Aqueous Extracts of the Leaf and Flower of Blumea Aurita. NIPES JSTR SPECIAL ISSUE, 7 (1). pp. 2101-2106.
Full text not available from this repository.Abstract
This study investigates the qualitative and quantitative phytochemical composition, GC-MS profile, and antibacterial activity of aqueous extracts from the leaf and flower of Blumea aurita, a plant widely recognized in traditional medicine. The phytochemical screening revealed the presence of key bioactive compounds, including alkaloids, flavonoids, saponins, and terpenes—all known for their therapeutic significance. Quantitative analysis showed relatively balanced concentrations of these metabolites in the leaf extract, with alkaloids (0.88 mg/100 g) being the most abundant, followed closely by terpenes (0.798 mg/100 g), flavonoids (0.789 mg/100 g), and saponins (0.78 mg/100 g). GC-MS analysis identified 23 bioactive compounds, with squalene (25.25%), octacosane (9.07%), and 2,6-dimethyl-6 nitro-2-hepten-4-one (8.37%) as dominant constituents, many of which have documented antimicrobial properties. Antibacterial assays demonstrated that the extract exhibited considerable inhibitory effects against Gram-negative Escherichia coli and Pseudomonas aeruginosa, as revealed by their zones of inhibition, suggesting the presence of synergistic phytochemical interactions that enhance antibacterial efficacy. These findings validate the traditional use of B. aurita leaves and flowers in managing infections and highlight their potential as a source of natural antibacterial agents. The integration of phytochemical profiling in this work provides a scientific foundation for future pharmacological development and supports the role of Blumea aurita as a promising candidate in the search for plant-based therapeutics amidst growing concerns over antibiotic resistance.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > QD Chemistry Q Science > QR Microbiology |
| Depositing User: | DR AKINYOMADE OWOLABI |
| Date Deposited: | 16 Feb 2026 09:13 |
| Last Modified: | 16 Feb 2026 09:13 |
| URI: | https://eprints.lmu.edu.ng/id/eprint/5923 |
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