Computational Prediction of Corynebacterium matruchotii Protein’s 3D Structure Reveals its Capacity to bind to DNA domain site in the Malaria Vector, Anopheles

Adebiyi, Marion and Falola, Damilare and Okesola, Olatunji and Ogundokun, Roseline Oluwaseun and Adeniyi, A. E. (2019) Computational Prediction of Corynebacterium matruchotii Protein’s 3D Structure Reveals its Capacity to bind to DNA domain site in the Malaria Vector, Anopheles. International Journal of Engineering Research and Technology, 12 (11). pp. 1935-1940. ISSN 0974-3154

Text Computational Prediction of Corynebacterium matruchotii_2019.pdf - Published Version Download (266kB)

Abstract

The production of proteins in our body system is controlled by the presence of transcriptional regulators. Transcriptional regulation is a mechanism that allows the translation of selected proteins to stop when they are not required or surplus in the body system. Corynebacterium matruchotii is a redox-responsive transcriptional regulator. Corynebacterium matruchotii is a protein inferred from homology and has a very short sequence of length 86. This protein was implicated in the work of Adebiyi, 2014 where it was predicted to be an insecticide target (after estimating it’s likely success in crystallization) i.e. estimating the protein’s propensity to produce the diffraction quality crystal which was the measure used in selecting best target.

Actions (login required)

View Item