Studies on the serological markers for hepatitis B virus infection among type 2 diabetic patients

Ndako, James A. and Nwankiti, Obinna O. and Olorundare, Joy O. and Ojo, Stephen K.S. and OKOLIE, CE and Olatinsu, Oludolapo and Dojumo, Victor T. (2021) Studies on the serological markers for hepatitis B virus infection among type 2 diabetic patients. Journal of Clinical Laboratory Analysis, 35 (1). ISSN 0887-8013

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Background: Hepatitis B infection is a public health concern globally. HBV can be as- sociated with type II diabetes mellitus, as HBV outbreaks have been observed among diabetics in healthcare facilities. This study evaluates the prevalence of HBV infec- tion among patients with type II diabetes mellitus. Method: A total of one hundred and eighty (180) diabetic patients and one-hundred non-diabetics (Controls) were recruited forthis study. Structured questionnaires were administered to the consented participants to obtain relevant data. Sera samples ob- tained were screened using the HBsAg ELISA kit; CTK Biotech, Inc, while the 5 panel kit—rapid diagnostic test, was used to assay for serological markers. Questionnaires were used to obtain relevant information and demographic data. Result: Overall prevalence of HBV infection among diabetes patients was 13.3%. Breakdown showed 9 (5.0%) seropositivity was obtained among male subjects com- pared to 15(8.3%) recorded among the females, P = .834; P < .05. Subjects aged 41-50 years recorded, 7(3.9%) positivity P = .774; P > .05. Educational status of par- ticipants showed 22 (12.2%) positivity among subjects with tertiary level of educa- tion P = .032; P < .05). Risk factors considered showed that 5(2.8%).seropositive subjects were alcoholic consumers (P value = .9711; P > .05). Result among non-di- abetics (Control) subjects showed (4%) seropositivity among the male subjects com- pared to (5.0%) seropositivity recorded among the female subjects (P = .739; P > .05). Conclusion: There is an indication of higher risk of HBV infection among type 2 dia- betic patients when compared to non-diabetics. There is the need for more research on this area of study, to further validate the association between HBV infection and Diabetes Mellitus.

Item Type: Article
Subjects: Q Science > QR Microbiology
Date Deposited: 29 Jun 2021 12:05
Last Modified: 29 Jun 2021 12:05

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