Chromatographic Fractionation of An Ethanolic Extract of Peels from Ipomoea batatas Lam for Improved Anticancer Activity

Oluyori, Abimbola and Olatunji, Gabriel Ademola and Shaw, Arun K. and Rastogi, P. and Sanjeev, Meena and Dipak, Datta (2019) Chromatographic Fractionation of An Ethanolic Extract of Peels from Ipomoea batatas Lam for Improved Anticancer Activity. ONCOGEN JOURNAL, 2 (1).

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Abstract

In this current work, the n-hexane fraction from an ethanolic extract of pulverized peel of Ipomoea batatas Lam was subjected to chromatographic fractionation. Consequently, the fractions were investigated for their anticancer potential using the Sulforhodamine-B assay. Chromatographic fractionation led to n-hexane sub-fractions with greater anticancer potential. The study highlights the peel of Ipomoea batatas Lam as a rich dietary source of natural anticancer molecules which may be developed into nutraceuticals or serve as new leads in anticancer therapy. Keywords: Ipomoea batatas; Chromatography; Fractionation; Anticancer; Sulforhodamine-B

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