Radiative Microwave Heating of Hyperthermia Therapy on Breast Cancer in a Porous Medium

Oke, Segun Isaac and Salawu, S. O. and Matadi, Maba B and Animasaun, Isaac L. (2018) Radiative Microwave Heating of Hyperthermia Therapy on Breast Cancer in a Porous Medium.

Text preprints201810.0313.v1.pdf - Published Version Download (1MB)

Abstract

Cancer is a leading cause of morbidity and mortality worldwide, yet much is still unknown about its mechanism of establishment and destruction. Recently, studies had shown that tumor cells cannot survive under the high temperature conditions. This treatment technique is called Hyperthermia. This report presents the case of radiative microwave heating of hyperthermia therapy on breast cancer in a porous medium. In this study, the steady state is solved analytically while unsteady state is solved using semi-implicit finite difference to get a more accurate prediction of blood temperature distributions within the breast tissues. A moderate temperature hyperthermia treatment is apply which results into cell death due to an increase in the level of cell sensitivity to radiation therapy and blood flow in tumor and oxygen. The results show that by applying metabolic heat generation rate of 3.97X105Wm−3, it takes upto 2 minutes for the tumor cells to get the require therapeutic temperature point

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