In Vivo Toxicity Studies and Phytochemical Screening of Stem Bark of Ficus Sycomorus Linn (Moraceae)

Bello, O.M. and Ojediran, J. O. and Dada, Adewumi O. and Olatunya, A.M. and Awakan, O. J. (2015) In Vivo Toxicity Studies and Phytochemical Screening of Stem Bark of Ficus Sycomorus Linn (Moraceae). IOSR Journal of Environmental Science, Toxicology and Food Technology (IOSR-JESTFT), 9 (3). pp. 72-74. ISSN 2319-2399

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Abstract

This research paper has investigated the In vivo toxicity studies and phytochemical screening of Stem bark of Ficus sycomorus Linn (Moraceae). Ethno-pharmacological relevance of Ficus sycomorus is quite obvious. It finds relevance in the treatment of Diabetes mellitus and other infectious diseases in the Northern part of Nigeria. The preliminary phytochemical screening of the extract revealed the presence of flavonoids, glycosides, reducing sugars, resins, saponins and tannins. The result of the experimental study carried out on albino rat which is close to human being indicates that stem bark extract of F. sycomorus produces toxicity at a dose of 1500 mg/kg. The outcome of this study offers support to the Ethno-medicinal uses of F. sycomorus in the treatment of various ailments. Keyword: F. sycomorus, Phytochemical, Saponins, flavonoids, glycosides, reducing sugars and Toxicity

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