Detection of Hepatitis C Virus (HCV) antibodies among HIV Seropositive women attending a Rehabilitation centre.

Ndako, James A. and Onwuliri, E.A. and Olopade, Bunmi K. and Olaolu, D.T. and Ifeanyi, Ilochi and Awakan, O. J. and Dojumo, Temitope V. and Ogido, Deborah O. (2014) Detection of Hepatitis C Virus (HCV) antibodies among HIV Seropositive women attending a Rehabilitation centre. IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS), 9 (3). pp. 40-44. ISSN 2278-3008

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Abstract

Co-infection with human immunodeficiency Virus HIV and (HCV) is becoming a major global problem, leading to increased morbidity and mortality in both developed and developing countries. This research hence examines the risk factors and transmission of HIV and HCV co-infection. Two hundred and ninety (290) subjects were screened, with HCV global immunochromatographic test kit. Possible risk factors to co-infectious status of subject were determined using a well-structured questionnaire. Out of the 290 sera tested, 25 (8.6%) were positive for HCV antibodies. Considering Age of subjects screened, females aged 11-20 years recorded a high positivity of 3.1 %,( X2 = 2.755, P-value = 0.839; P>0.05).Marital status of subjects showed that single subjects recorded 13(4.5%), (X2 = 0.679,P-value = 0.712 ; P > 0.05)positivity compared to married subjects with 4.1%. There were no significant correlations between HCV infection with Age and Marital Status; P - values = 0.839 and 0.712 respectively (i.e P > 0.05). Significant correlation was found between HCV antibodies and educational status, (Value x2 = 7.957,P-value = 0.047; P < 0.05).However, Volunteers with secondary school level of education recorded 10(3.4%) positivity. The result obtained showed that Seroprevalence to HCV antibodies in this study was high, hence the need for its early diagnosis among HIV patients is strongly advocated to reduce the risk of further complications among these subjects.

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