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Natural Product Research: Formerly Natural Product Letters

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Natural antifungal compounds from the peels of Ipomoea batatas Lam
Short Communication

Natural antifungal compounds from the peels of Ipomoea batatas Lam

DOI:
10.1080/14786419.2015.1113413
Abimbola P. Oluyoria*, Arun Kumar Shawb, Rastogi Preetib, Sammajay Reddyb, Olubunmi Atolanic, Gabriel A. Olatunjid & Oluwatoyin A. Fabiyie

Abstract

Three antifungal compounds have been isolated for the first time from the peels of Ipomoea batatas Lam. Their structures were established on the basis of 1D and 2D NMR spectra data as well as ESI-MS and IR analysis. Urs-13(18)-ene-3β-yl acetate was found to possess a weak activity against Sporothrix schenckii and Trichophyton metagrophytes fungi with an MIC value of 50 μg/mL each. Stigmasterol and 3-friedelanol were equally active against T. metagrophytes.

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Details

  • Received: 22 May 2015
  • Accepted: 29 Aug 2015
  • Published online: 23 Nov 2015

Author affiliations

  • a Department of Physiscal Science, Landmark University, Omuaran, Nigeria
  • b Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow, India
  • c Department of Chemistry, University of Ilorin, Ilorin, Nigeria
  • d Department of Industrial Chemistry, University of Ilorin, Ilorin, Nigeria
  • e Department of Crop Protection, University of Ilorin, Ilorin, Nigeria

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  • 2014 Impact Factor 0.919 (©2014 Thomson Reuters, 2014 Journal Citation Reports®)

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